While raising three children and taking care of the household, Fanny Angelina Hesse supported, documented, and archived her husband’s work, creating stunning scientific illustrations of bacterial and fungal colonies. During the hot Summer of 1881, she watched as Hesse struggled with gelatine-based growth media. Fanny Angelina, recalling the stability of her agar-based desserts, suggested that they try that instead. Hesse wrote a letter to Koch informing him about the switch, and Koch mentioned agar for the first time in his 1882 groundbreaking paper on the discovery of the tuberculosis bacillus.
心理建设、家庭配合心理建设我的理解是要让孩子提前做好心理准备，这需要全家的配合。首先要跟孩子说明，我们马上要上幼儿园了，要早起，所以我们要跟妈妈起床时间一样，告诉孩子时间是8点钟（顺便用家里的钟表简单告诉她什么是8点钟），然后洗漱吃饭，再自己选择想穿的衣服（我会告诉她天晴情况，让她自己选，如果有问题，我再调整），自己穿衣服，然后出门玩耍或者去爷爷奶奶家。
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